Effect of Epinephrine on Systemic Absorption of Mepivacaine in Uremic Patients

• Status: Terminated
• Trial end date: 2014-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study is to determine the effect of epinephrine on systemic absorption of local anaesthetic mepivacaine administered for brachial plexus block in uremic patients scheduled for creation or repair of an arteriovenous fistula. Furthermore, an impact of epinephrine on the central circulation and peripheral tissue oxygenation will be evaluated.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Rigshospitalet, Denmark
• Treatments: Epinephrine; Epinephryl borate; Mepivacaine; Racepinephrine

Criteria

Inclusion Criteria:

• patient acceptance of regional anaesthesia

Exclusion Criteria:

• peripheral arteriosclerosis

• diabetes mellitus

• bleeding disorder

• infection at the puncture site

• allergy to mepivacaine

• pregnancy