Effect of Epigallocatechin-Gallate on Inner Retinal Function in Ocular Hypertension and Early Glaucoma

• Status: Unknown status
• Trial end date: 2008-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The present study attempts to evaluate the potential beneficial effects of a flavonoid, the epigallocatechingallate, on retinal ganglion cell function, evaluated by pattern electroretinogram, in subjects with ocular hypertension or early glaucoma.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Catholic University of the Sacred Heart
• Treatments: Epigallocatechin gallate

Criteria

Inclusion Criteria:

• IOP > 21 mmHg at the time of diagnosis

• Response to ipotensive therapy

• No visible alterations of the optical nerve head (if OHT)

• Visual field: normal (if OHT), < -6dB at diagnosis (if POAG)

• Alterations in PERG

• Familiarity for glaucoma (if OHT)

Exclusion Criteria:

• Change of ipotensive therapy

• Ocular surgery

• Other ocular pathologies

• Smokers