Effect of Enamel Matrix Proteins on Clinical Attachment Level and Alveolar Bone in Periodontal Maintenance Patients

• Status: Completed
• Trial end date: 2018-09-20
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine the effect of enamel matrix protein derivative on an inflamed, periodontal-involved tooth. The hypothesis to be studied is that enamel matrix derivative protein with increase the clinical attachment level is localized sites of advanced periodontal disease.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Nebraska

Criteria

Inclusion Criteria:

• diagnosis of chronic advanced adult periodontitis

• one quadrant with at least one 6-9 mm interproximal pocket

• overall good systemic health

• willingness to sign consent form

Exclusion Criteria:

• systemic diseases which significantly impact periodontal inflammation and bone turnover (e.g. rheumatoid arthritis)

• taking drugs which significantly impact periodontal inflammation and bone turnover

• surgical periodontal therapy within the past year

• pregnant or breast-feeding females