Effect of Early High-dose Epoetin Alfa During Cardiac Arrest (Pilot Study)

• Status: Completed
• Trial end date: 2004-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to test the possible neuroprotective effect of early high dose erythropoietin alpha after out of hospital cardiac arrest (OHCA).

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Janssen Cilag S.A.S.

Criteria

Inclusion Criteria:

• Patients who have OHCA of presumed cardiac origin

• Patient's who have delay between the collapse and onset of cardiopulmonary resuscitation (CPR, no flow) less that 10 minutes

• Patient's who have delay between onset of CPR and return of spontaneous circulation (ROSC, low flow) less than 50 minutes

• Patient's who have persistent coma with Glasgow Coma Scale (CGS) less that 7 after ROSC

Exclusion Criteria:

• Patient's who have cardiac arrest of non-cardiac aetiology

• Patient who have previous EPO treatment

• Patient's who are in pregnancy stage

• Patient's who have evidence of rapidly fatal underlying condition