Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty
Status:
Completed
Trial end date:
2021-02-10
Target enrollment:
Participant gender:
Summary
Post-discharge pain after total knee arthroplasty remains problematic; many patients have
excessive pain at the 2 week time point (and often thereafter). Reduction in opioid use has
become a national goal, due to the 'epidemic' in opioid misuse.
In addition to enrolling non-opioid users, we will enroll up to 15 chronic opioid users.