Effect of Different Therapeutic Strategies on Regulatory T Cells in Kidney Transplantation
Status:
Completed
Trial end date:
2014-04-01
Target enrollment:
Participant gender:
Summary
The objective of the study will be to evaluate the effect of different therapeutic
immunosuppressive strategies currently employed in common clinical practice on regulatory T
lymphocytes and to verify the hypothesis that the association of thymoglobulins - mTOR
inhibitors - small doses of Tacrolimus not only represents a safe anti-rejection therapy but
it can also lead to mid-term formation of a high amount of regulatory T cells and,
consequently, a high grade of tolerance.