Effect of Different Heparinization Schemes on Prognosis of Intracranial Aneurysm
Status:
Not yet recruiting
Trial end date:
2024-04-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical trial is to compare intracranial aneurysm patients. The main
question it aims to answer are: Which heparinization regimen is most beneficial to patients
during surgery for intracranial aneurysms. Participants will be randomized to different
intraoperative heparinization regimens: (i) 50 U/kg intravenous (IV) at 1-h intervals reduced
by half to a minimum of 1000 u/h; (ii) 60 U/kg IV at 1-h intervals reduced by half to a
minimum of 1000 u/h; (iii) 70 U/kg IV at 1-h intervals reduced by half to a minimum of 1000
u/h. MRI will be performed within 72 h after surgery, and the DWI sequence of MRI will be
analyzed. If there is a comparison group: Researchers will compare different intraoperative
heparinization protocol groups to see which dose of intraoperative heparin has the best
prognosis for use.
Phase:
N/A
Details
Lead Sponsor:
The First Affiliated Hospital with Nanjing Medical University