Effect of Different Anesthetics on the Change of Alarmins in Lung Cancer Patients Receiving Pulmonary Lobectomy
Status:
Unknown status
Trial end date:
2019-01-01
Target enrollment:
Participant gender:
Summary
This study aim to observe and compare the change of alarmins such as high mobility group
nucleosome-binding protein-1 (HMGN1), high mobility group proteins b1 (HMGb1), Interleukin
(IL)-33 and their soluble receptors including soluble toll like receptor 4 (sTLR4) and
soluble ST2 (sST2) during pulmonary lobectomy for cancer patients receiving volatile
anesthesia or intravenous anesthesia under one-lung ventilation (OLV). By which, this study
will preliminarily evaluate the correlation of alarmins and prognosis as well as the effect
of inhalational and intravenous anesthesia on the prognosis of surgical patients.
Phase:
N/A
Details
Lead Sponsor:
Tianjin Medical University Cancer Institute and Hospital