Effect of Dexmedetomidine on Sevoflurane Requirements and Emergence Agitation in Children Undergoing Ambulatory Surgery
Status:
Completed
Trial end date:
2012-03-01
Target enrollment:
Participant gender:
Summary
Although the aetiology of emergence agitation (EA) derives from multiple factors, it is a
frequent side effect of sevoflurane anaesthesia in children. Dexmedetomidine, a potent
selective α2-adrenergic agonist, can reduce the doses of hypnotics, opioids, analgesics, and
anaesthetics that must be concomitantly administered. This study was conducted to assess the
effect of dexmedetomidine infusion on sevoflurane requirements and recovery profiles with EA
in children undergoing ambulatory surgery.