Effect of Dexmedetomidine on Renal Function and Delayed Graft Function After Kidney Transplantation

• Status: Unknown status
• Trial end date: 2019-09-28
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to elucidate the effect of dexmedetomidine on renal function and delayed graft function after kidney transplantation

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Yonsei University
• Treatments: Anesthetics; Dexmedetomidine

Criteria

Inclusion Criteria:

1. adult (20-80 years old)

2. patients undergoing elective kidney transplantation

Exclusion Criteria:

1. emergency surgery

2. severe sinus bradycardia (<50 beats per min [bpm])

3. second-degree or third-degree heart block

4. decreased heart function (EF <30%)

5. acute myocardial ischemia

6. serious hepatic dysfunction (Child-Pugh class C)

7. patients with known or suspected severe adverse reactions to DEX (or clonidine)

8. treatment with clonidine or dexmedetomidine in the past 30 days