Effect of Dexmedetomidine on Recovery Profiles of Elderly Patients

• Status: Completed
• Trial end date: 2014-02-01
• Target enrollment: 0
• Participant gender: All

Summary

Emergence of elderly patients from anesthesia may face with cognitive dysfunction or agitation such as delirium. There are reports that using dexmedetomidine as a adjuvant for general anesthesia decreased emergence-agitation in children and dexmedetomidine may be used for treating deliriums. Thus, we thought that dexmedetomidine as a adjuvant agent may be a help to smooth emergence from anesthesia in elderly.

The aims of this study were to investigate the recovery characteristics (time to recovery of consciousness (ROC) and recovery, bispectral index (BIS) values at ROC and orientation, and Ricker sedation-agitated scale at the postanesthetic care unit) and safety (vital signs during and after administration of dexmedetomidine) of dexmedetomidine in elderly patients undergoing elective surgery.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Chosun University Hospital
• Treatments: Anesthetics; Dexmedetomidine; Propofol; Remifentanil; Rocuronium; Sevoflurane

Criteria

Inclusion Criteria:

• ASA I-II

• Age > 65

• Elective surgery

Exclusion Criteria:

• Patients with severe heart disease with New York Heart Association class > III

• Patients with severe arrhythmia

• Patients with uncontrolled hypertension or hypotension

• Patients with hemodynamic unstably

• Patients with hypersensitivity with drugs

• Patients with cognitive deficiency, dementia, or delirium

• Patients with hepatic or renal compromise

• Patients with infective disease