Effect of Dexmedetomidine Upon Sleep Postoperatively

• Status: Withdrawn
• Trial end date: 2011-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine whether an intravenous infusion of dexmedetomidine administered to surgical patients intra-operatively will improve the characteristics of sleep post-operatively.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Duke University
• Treatments: Dexmedetomidine; Fentanyl; Isoflurane; Midazolam; Propofol

Criteria

Inclusion Criteria:

• scheduled to undergo elective lower extremity orthopaedic surgery (free vascular fibular graft)

• ASA 1 or 2

• Body Mass Index 20 - 30

• Procedure to be done under combined epidural and general anesthesia

Exclusion Criteria:

• Sleep disturbance

• Insomnia

• Sleep apnea

• Female (pregnant)

• Contra-indication to placement of epidural anesthesia