Overview

Effect of Dexamethasone on Labour Induction in Term Pregnancies

Status:
RECRUITING
Trial end date:
2025-09-15
Target enrollment:
Participant gender:
Summary
The aim of the study is to assess the effect of dexamethasone on labour induction in term pregnancies. Primary outcome: The interval between initiation of induction and beginning of the active phase of labour. Secondary outcomes: * Duration of active phase of labour (starting with cervical dilatation of 4-5 cm up to full cervical dilatation). * Duration of second stage of labour * Mode of delivery. * Fetal outcome. Group A: Will receive one dose of IM dexamethasone sodium phosphate 8 mg (2 mL). Group B: Will receive vaginal misoprostol 25 g tablets every 6 h, up to 4 tablets, for a maximum duration of 24 h. Group C: Will receive one dose of IM dexamethasone sodium phosphate 8mg (2mL) with the first dose of vaginal misoprostol 25 g tablets that will be given every 6 h, up to 4 tablets, for a maximum duration of 24 h.
Phase:
EARLY_PHASE1
Details
Lead Sponsor:
Cairo University
Treatments:
Calcium Dobesilate
Dexamethasone
Injections, Intramuscular
Misoprostol