Effect of Desflurane on Cardiac Function During Cardiac Surgery: Tissue Doppler Imaging of Mitral Valve Annular Velocity

• Status: Unknown status
• Trial end date: 2015-09-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine desflurane's dose-dependent effect on left ventricular (LV) function in cardiac surgery. The change of tissue Doppler imaging (TDI) of lateral mitral valve annular velocity at three different desflurane concentrations would be analyzed by using intraoperative transesophageal echocardiography (TEE) in cardiac surgery patients

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Konkuk University Medical Center
• Treatments: Desflurane; Isoflurane; Remifentanil

Criteria

Ages eligible for study : 20 years to 65 years Genders eligible for study : Both

Inclusion Criteria:

• Patients undergoing cardiac surgery

Exclusion Criteria:

• Low ejection fraction <50% in preoperative transthoracic echocardiography

• Atrial fibrillation

• Pacemaker

• Pericardial and infiltrative myocardial disease

• Mitral annular calcification, surgical rings, prosthetic mitral valves

• Lateral left ventricular regional wall motion abnormality

• Esophageal spasm, stricture, laceration, perforation, and diverticulum

• Diaphragmatic hernia

• History of extensive radiation to mediastinum

• Upper gastrointestinal bleeding