Effect of Dapagliflozine on Systemic and Renal Endothelial Function
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
This is a phase 4, single center, randomized, open-labeled, cross-over design study. The
primary objective of the study is to compare effect of dapagliflozine and metformin on
endothelial function.
Subjects are randomized to initial metformin or initial dapagliflozin group and maintained
initial treatment for 8 weeks. During that period, dose of dapagliflozin is maintained
10mg/day and metformin can be titrated upto 2000 mg/day. After 1 weeks of washout period, 8
weeks' cross-over is followed.