Effect of Daily Use Proton Pump Inhibitors for One Month on Kidney Function

• Status: Unknown status
• Trial end date: 2021-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of this study to: evaluate the association between prolonged use of PPI and adverse renal outcomes on patients with normal renal function and others with abnormal renal function

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Assiut University
• Treatments: Pantoprazole; Proton Pump Inhibitors

Criteria

Inclusion Criteria:

• patients with peptic ulcer disease or gastroesophagial reflux with normal l renal function

• patients with peptic ulcer disease or gastroeosophagial reflux with abnormal renal function

Exclusion Criteria:

• 1- cigarette smoker: Cigarette smoking status was defined categorically as current,former, or never smoker at baseline.

2-biabetic patients: diabetes mellitus is defined by a fasting blood glucose concentration >_ 126 mg/dl ,random glucose level of >200 mg/dl.

3-patients take corticosteroid 4-patients with hypersensitivity to these drugs