Overview

Effect of Combination of Mitiglinide and Metformin on Glycemic Control in Patients With Type 2 Diabetes Mellitus

Status:
Completed
Trial end date:
2008-05-01
Target enrollment:
Participant gender:
Summary
We performed a prospective, randomized, multicenter trial to assess the efficacy and safety of combined treatment with mitiglinide and metformin for patients with type 2 diabetes who show inadequate glycemic control with metformin monotherapy. Subjects with HbA1c >7.0% after an 8-week metformin run-in phase were randomized to a 16-week trial phase with metformin plus mitiglinide (Met+Mit) or metformin plus placebo (Met).
Phase:
Phase 3
Details
Lead Sponsor:
Seoul National University Hospital
Collaborators:
Chonbuk National University
Chonnam National University
Chungnam National University
Eulji University
Hallym University
Korea University
Kyungpook National University
Kyungpook National University Hospital
Pusan National University College of Medicine
Seoul St. Mary's Hospital
Sungkyunkwan University
The Catholic University of Korea
Uijeongbu St. Mary Hospital
Yonsei University
Treatments:
Metformin
Mitiglinide