Effect of Colony Stimulating Factor on Poor Endometrial Development During IVF

• Status: Terminated
• Trial end date: 2013-02-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to investigate the effect of G-CSF on endometrial thickness in women who have failed reaching minimal endometrial thickness by standard treatments, to assess how many reach embryo transfer and what implantation and pregnancy rates are in comparison to control patients. The study will be conducted in women undergoing transfer of previously cryopreserved embryos or undergoing transfer of embryos from donor eggs.

• Phase: Phase 1/Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Center for Human Reproduction
• Collaborator: Foundation for Reproductive Medicine
• Treatments: Lenograstim

Criteria

Inclusion Criteria:

• Patient's preparing for invitro fertilization and embryo transfer with endometrial growth of less than 7 mm, unresponsive to standard treatment

Exclusion Criteria:

• Sickle Cell disease

• Renal insufficiency

• Upper respiratory infection or Pneumonia

• Chronic Neutropenia

• Known Past or present malignancy