Overview

Effect of Colony Stimulating Factor on Implantation and Pregnancy Rates Following IVF (in Vitro Fertilization)

Status:
Completed
Trial end date:
2013-06-01
Target enrollment:
0
Participant gender:
Female
Summary
This a trial designed to test whether granulocyte colony stimulating factor (G-CSF, Neupogen) can increase the rate of embryo implantation following IVF and embryo transfer. Preliminary data at the Center for Human Reproduction(CHR) and elsewhere suggest that intrauterine infusion of G-CSF can improve endometrial development and can increase implantation rates of embryos.
Phase:
Phase 1/Phase 2
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Center for Human Reproduction
Collaborator:
Foundation for Reproductive Medicine
Treatments:
Lenograstim
Criteria
Inclusion Criteria:

- Women already enrolled in an IVF cycle at one of the participating institutions

Exclusion Criteria:

- Sickle Cell disease

- Renal insufficiency

- Upper respiratory infection or Pneumonia

- Chronic Neutropenia

- Known Past or present malignancy