Effect of Clopidogrel on Allergen Challenge in Asthma
Status:
Unknown status
Trial end date:
2014-05-01
Target enrollment:
Participant gender:
Summary
In asthma, breathing in an allergen, such as house dust mite induces inflammation in the
airways. This process appears to involve an interaction between two different sorts of blood
cells, platelets and white blood cells via a receptor called the P2Y12 receptor. The purpose
of this study is to determine whether the drug clopidogrel which blocks the P2Y12 receptor on
platelets, reduces inflammation following breathing in house dust mite in people with mild
asthma.