Effect of Citalopram on Chest Pain in Patients With Functional Chest Pain
Status:
Terminated
Trial end date:
2022-04-22
Target enrollment:
Participant gender:
Summary
Non-cardiac chest pain (NCCP) in the absence of musculoskeletal abnormalities, major
esophageal motor disorders, gastroesophageal reflux or eosinophilic esophagitis is called
functional chest pain (FCP). Most likely multiple factors play a role, such as esophageal
hypersensitivity and enhanced perception. Citalopram and other antidepressants are proven to
be effective in the treatment of functional gastrointestinal disorders such as irritable
bowel syndrome. With this trial the investigators want to assess the effect of citalopram on
symptoms of chest pain in patients with functional chest pain.
Phase:
Phase 4
Details
Lead Sponsor:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)