Effect of Ciclosporin Eyedrops on Sjögren Syndrome
Status:
Completed
Trial end date:
2021-03-31
Target enrollment:
Participant gender:
Summary
Keratoconjunctivitis sicca, also known as dry eye syndrome, is one of the most common
ophthalmological diseases and is treated with tear substitutes to moisten the surface of the
eye and, in more severe cases of this disease, with local anti-inflammatory therapy with
corticosteroids or ciclosporin A. In patients with rheumatological diseases, such as
Sjögren's syndrome, dry eye syndrome of severe extent occurs particularly frequently, which
is why topical anti-inflammatory therapy is often necessary in these patients.
Aim of this study is to evaluate the treatment of severe dry eye syndrome with topical
cyclosporin eyedrops with and without topical corticosteroids at the beginning of the
treatment.