Effect of Celery Seed on the Components of Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion
Status:
Recruiting
Trial end date:
2025-12-01
Target enrollment:
Participant gender:
Summary
The Metabolic Syndrome (MS) is a cluster of cardiometabolic risk factors, which include
abdominal obesity, hyperglycemia, dyslipidemia, and high blood pressure. MS is a global
health problem, it represents a risk factor for the progression of cardiovascular disease,
which constitute the main cause of mortality in the world and in Mexico. The current
treatment involves lifestyle changes and pharmacological treatment for each of the components
of MS, however, there is no single approved treatment to control all components. Celery seed
(Apium graveolens L.) from the Apiaceae family contains the flavonoids apigenin and luteolin;
essential oils such as d-limonene, selinene and phthalides such as 3-n-butylphthalide. Thanks
to its bioactive components, celery seed has proven to be effective in treating individual MS
disorders; however, most studies are in animal models and there are no clinical studies that
evaluate its effectiveness on all components of the system. MS, insulin sensitivity and
insulin secretion so it could appear as a new, safe and effective complementary therapy for
the treatment of MS.
The aim of this study is to evaluate the effect of celery seed on the components of metabolic
syndrome, insulin sensitivity, and insulin secretion.