Effect of Carvedilol Rapid Up-Titration in Patients With Heart Failure With Reduced Ejection Fraction
Status:
Recruiting
Trial end date:
2022-03-30
Target enrollment:
Participant gender:
Summary
Guidelines-directed medical therapy has improved dramatically outcomes in heart failure with
reduced ejection fraction (HFrEF) patients. Beta-blockers have the most beneficial effects on
all caused mortality and rehospitalization on HFrEF, but unfortunately, since the discovery
of beta-blocker therapy in HFrEF, there was no change in the way of titration, start low go
slow, which resulted in difficulties in reaching optimal doses for some patients.