Effect of Calcium + Vitamin D Supplementation on Weight Management in Very-low Calcium Consumers

• Status: Completed
• Trial end date: 2012-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of the study is to determine whether calcium plus vitamin D supplementation is conducive to weight and fat loss during energy restriction in very-low calcium consumers.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Changhai Hospital
• Treatments: Calcium; Calcium Carbonate; Calcium, Dietary; Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Male or female 18 to 25 years of age, generally healthy

• Habitual calcium intake below 600mg/d

• Overweight or obese (BMI between 24 and 35kg/m2, refer to the Chinese standard)

• Stable body weight (body weight change less than 1kg two months before screening)

• Less than 3 times of 20min of physical exercise per week

• Signed written informed consent

Exclusion Criteria:

• Coronary heart disease, hypertension, diabetes; hepatic insufficiency or renal insufficiency, hyper- or hypothyroidism, mal-absorption, cholesterol concentrations requiring pharmaceutical treatment

• Pregnant or lactating woman

• Use of calcium supplements, oral antidiabetic agents, antihyperlipidemics or any other medications affecting metabolism 30 days before randomization

• Participating in another weight loss programs (i.e. taking oral pharmacotherapeutic agents and/or herbal preparations intended for the management of obesity; excessive physical activity; be on a diet)

• On special diets (i.e. vegetarian)

• Presently taking or have recently taken a prescription drug such as fluoroquinolone antibiotics, tetracycline, or levothyroxine (thyroid medication)

• Participating in another clinical trial 6 months before randomization

• Unlikely to be compliant (i.e. alcohol, drug abuse)

• Refusal or inability to give informed consent to participate in the study