Effect of Calcium Silicate Based Root Canal Medicament on Inflammatory Mediators
Status:
COMPLETED
Trial end date:
2023-12-10
Target enrollment:
Participant gender:
Summary
Calcium hydroxide is generally preferred in endodontics as an intracanal medicament because of its antimicrobial and biological effects. However, the antimicrobial effect of calcium hydroxide is limited.
The aim of this study was to investigate the effects of calcium silicate-based root canal medicament on the release of RANKL/OPG, TNF-α, PGE-2 and TGF-β1 in root canal treated teeth with periapical lesions.