Overview

Effect of Cabergoline on Weight and Glucose Tolerance

Status:
Completed
Trial end date:
2011-07-01
Target enrollment:
0
Participant gender:
All
Summary
The aim of this study is to determine the efficacy of cabergoline, a long-acting dopamine receptor agonist, on body weight and blood glucose in healthy obese adults. This is a randomized double-blind placebo controlled study. Twenty subjects each will be randomly assigned either placebo or cabergoline for 16 weeks. The effect of treatment on body weight and blood glucose and insulin levels will be compared in the treatment versus the placebo arm.
Phase:
Phase 1/Phase 2
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Columbia University
Treatments:
Cabergoline
Criteria
Inclusion Criteria:

- age 18 - 55 years

- BMI 30 -40

Exclusion Criteria:

- diabetes,

- clinically significant medical condition,

- use of medications that effect blood glucose or body weight