Effect of Bupivacaine Application on Postthyroidectomy Pain

• Status: Completed
• Trial end date: 2011-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Investigators aimed to evaluate the impact of bupivacaine administration into the surgical field after total thyroidectomy on post-operative pain and analgesic requirement with a double-blind, prospective, clinical, randomized study.

Pain assessment was performed with the visual analog score (VAS). Participants were pre-operatively, divided into two groups randomly to receive either bupivacaine or not. One group received a 10 ml of bupivacaine solution while the other group was treated with the same volume of 0.9% sodium chloride (NaCl) through the drain after completion of total thyroidectomy procedure. All participants were anesthetized and operated with the same anesthesia and surgical team.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Istanbul University
• Treatments: Bupivacaine; Pharmaceutical Solutions

Criteria

Inclusion Criteria:

• Subjects need to be operated for thyroid diseases

Exclusion Criteria:

• History of previous thyroid disease,

• History of previous neck operations,

• Hypersensitivity to the drugs that were used in the study protocol,

• Spinal bone disease,

• Depression,

• Kidney failure,

• Heart failure,

• Liver failure,

• Pulmonary failure,

• Mental retardation,

• Subjects not able to ascertain pain scoring with the visual analog score (VAS),

• Patients with American Society of Anesthesiologists (ASA) scores III or higher,

• Expected airway difficulty according to Mallampati scores,

• Sedative, steroid, and chronic analgesic drug users,

• Alcoholics