Overview

Effect of Broccoli Sprout Extract on Keratinocyte Differentiation in Normal Skin

Status:
Completed
Trial end date:
2016-12-01
Target enrollment:
0
Participant gender:
All
Summary
Adult participants will apply a broccoli sprout extract-jojoba oil compound to one arm every night under occlusion for 1 week. Jojoba oil alone will be applied to the other arm. At the end of 1 week, a 6mm punch biopsy will be taken from both arms and analyzed via polymerase chain reaction (PCR) and immunohistochemistry for differences in various skin proteins.
Phase:
Phase 1
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Johns Hopkins University
Criteria
Inclusion Criteria:

- Able to attend 3 visits at the designated times.

Exclusion Criteria:

- Pregnant

- Known allergy to broccoli, lidocaine, or epinephrine