Effect of Botulinum Toxin to Hallux Valgus in Addition to Total Contact Insole
Status:
Completed
Trial end date:
2013-08-01
Target enrollment:
Participant gender:
Summary
The investigators propose a new therapeutic approach by injecting Botulinum Toxin Type A
(BTA) to the oblique and transverse heads of adductor muscle of the great toe. BTA works by
binding presynaptically to high-affinity recognition sites on the cholinergic nerve terminals
and decrease the release of acetylcholine, causing a neuromuscular blocking effect. The
investigators hypothesize that BTA injection may help to decrease the hallux valgus angle by
decrease adductor hallucis muscle activation. Thereby enhance the therapeutic result of
hallux valgus treated with total contact insole. The outcome measurement may shed light in
treating patient with painful hallux valgus and document evidence for plantar pressure
changes in acute, sub-acute and chronic stage.
Phase:
Phase 4
Details
Lead Sponsor:
Chang Gung Memorial Hospital
Collaborator:
National Science Council, Taiwan
Treatments:
abobotulinumtoxinA Botulinum Toxins Botulinum Toxins, Type A incobotulinumtoxinA onabotulinumtoxinA