Effect of Betablocker or Aldosterone Antagonist Therapy on Patients With Liver Cirrhosis

• Status: Unknown status
• Trial end date: 2010-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The study´s purpose is to investigate the effect of beta blockade or aldosterone antagonist therapy on oxygenation, peripheral and cardiac hemodynamics and humoral systems, in patients with liver cirrhosis.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hvidovre University Hospital
• Treatments: Adrenergic beta-Antagonists; Mineralocorticoid Receptor Antagonists; Propranolol; Spironolactone

Criteria

Inclusion Criteria:

• Liver cirrhosis

• Clinical indication for treatment with betablocker or aldosterone antagonist

• Must not have been treated earlier with betablocker or aldosterone antagonist

• Must have been alcohol abstinent for more than 4 weeks

Exclusion Criteria:

• Gastrointestinal bleeding in the last 2 weeks

• Encephalopathy > grade 1

• Acute medical conditions

• Malignant disease

• Pregnancy