Effect of Beetroot Juice on Coronary Blood Flow and Walking Performance in PAD
Status:
Recruiting
Trial end date:
2023-12-01
Target enrollment:
Participant gender:
Summary
In this study the investigators will test the hypothesis that short-term consumption of
inorganic nitrate (supplied in concentrated beetroot juice) enhances coronary blood flow
responses, large artery hemodynamics, and leg oxygenation/exercise tolerance in patients with
peripheral arterial disease (PAD). Understanding and improving blood flow regulation in the
heart and skeletal muscles of patients with PAD is important because exercise triggers
symptoms of leg pain and substantially raises blood pressure and myocardial demand in these
patients.
Phase:
Phase 2
Details
Lead Sponsor:
David N. Proctor David N. Proctor, PhD
Collaborators:
Milton S. Hershey Medical Center Wake Forest University Health Sciences