Overview

Effect of Antimalarial Drugs to Rabies Vaccine for Post-exposure Prophylaxis.

Status:
Completed
Trial end date:
2019-02-01
Target enrollment:
Participant gender:
Summary
This is an exploratory trial to evaluate the effect of antimalarial drugs on the immune response generated by rabies vaccine when administered for post-exposure prophylaxis. This study will use the FDA approved post-exposure prophylaxis vaccine regimen (without rabies immune globulin) in the presence or absence of an FDA-approved malaria chemoprophylaxis regimen.
Phase:
Phase 4
Details
Lead Sponsor:
State University of New York - Upstate Medical University
Collaborators:
Kansas State University
Walter Reed Army Institute of Research (WRAIR)
Treatments:
Antimalarials
Atovaquone
Atovaquone, proguanil drug combination
Chloroquine
Chloroquine diphosphate
Doxycycline
Proguanil
Vaccines