Overview

Effect of Antibiotics on Penile Microbiome and HIV Susceptibility Study in Ugandan Men

Status:
Unknown status
Trial end date:
2019-12-07
Target enrollment:
Participant gender:
Summary
This pilot study will assess the impact of four antimicrobial products (3 topical, one systemic) on the foreskin microbiome and HIV susceptibility of foreskin-derived CD4+ T cells. Participants will include HIV-uninfected Ugandan men presenting for elective male circumcision to reduce their HIV risk.
Phase:
N/A
Details
Lead Sponsor:
University of Toronto
Collaborators:
Entebbe General Hospital
UVRI-IAVI HIV Vaccine Program
Treatments:
Clindamycin
Clindamycin palmitate
Clindamycin phosphate
Hydrogen Peroxide
Metronidazole
Tinidazole