Effect of Anesthesia Technique on Outcome After Hip Fracture Surgery in Elderly Adult Patients
Status:
Completed
Trial end date:
2019-01-21
Target enrollment:
Participant gender:
Summary
Despite many previous studies, whether anesthetic technique will significantly affect overall
patient outcome, morbidity and mortality in elderly hip fracture patients is controversial.
Due to old age, poor patient condition and emergent clinical settings, patients undergoing
surgical procedures for hip fracture management are often subject to poor postoperative
outcome and high mortality rates. While many studies have reported that regional anesthesia
leads to improved postoperative outcome after hip fracture surgery, others have concluded
otherwise. Moreover, because the majority of these previous studies are retrospective cohorts
or systemic reviews, there is a need for randomized clinical trials to provide high quality
evidence. This study aims to compare patient outcome between three different anesthetic
techniques in elderly patients undergoing surgery for hip fracture management by evaluating
proinflammatory cytokines, chemistry lab testing and clinical outcome between general
anesthesia with either desflurane or propofol-based TIVA and spinal anesthesia with
bupivacaine.