Effect of Alprazolam on the Success of Inferior Alveolar Nerve (IAN) Block

• Status: Completed
• Trial end date: 2012-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this prospective, randomized, double-blind, placebo-controlled study is to evaluate the effect of preoperative administration of alprazolam on the success of the IAN block for teeth with irreversible pulpitis.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Isfahan University of Medical Sciences
• Collaborator: University of Isfahan
• Treatments: Alprazolam

Criteria

Inclusion Criteria:

• patients with active pain in a mandibular molar

• prolonged response to cold testing with Endo-Frost cold spray

• Absence of any periapical radiolucency on radiographs

• a vital pulp while access cavity preparation

• ability to understand the use of pain scales.

Exclusion Criteria:

• patients were having allergy and sensitivity to benzodiazepines

• pregnant and breast feeding patients

• patients who had taken sedation within 24 hours before the treatment

• having pain in more than one mandibular tooth

• unable to give informed consent