Effect of Alphagan and Xalatan Eye Drops on Corneal Temperature
Status:
Completed
Trial end date:
2013-11-01
Target enrollment:
Participant gender:
Summary
It is already known that the local treatment with Alphagan eye drops (a drug commonly used by
glaucoma patients) reduces ocular blood flow. In-vitro studies suggest that the
vasoconstrictive effect of Alphagan is more pronounced when this drug is combined with a
prostaglandin analogue (eg. Xalatan eye drops). The investigators also question whether this
effect is more pronounced in subjects suffering from a primary vascular dysregulation (PVD).
To test for the effect of these drugs on PVD and non-PVD subjects the investigators will take
measurements of corneal temperature as surrogate for ocular blood flow.