Effect of Alfacalcidol to Respiratory Infection and Immune Response of Indonesian Elderly
Status:
Unknown status
Trial end date:
2017-12-15
Target enrollment:
Participant gender:
Summary
Vitamin D has been known to influence immune response through Vitamin D Receptor in Immune
Cells, but only few has been known about the effect alfacalcidol, a vitamin D analog to
immune system. In elderly, immune disregulation or immunosenecence have great impact to
infection response. This study is aimed to determine the effect of alfacalcidol
supplementation in vitro and in vivo to respiratory infection incidence and inflammatory
markers, as well as T cell lymphocyte subset in Indonesian elderly patients.