Overview

Effect of Alfacalcidol to Respiratory Infection and Immune Response of Indonesian Elderly

Status:
Unknown status
Trial end date:
2017-12-15
Target enrollment:
0
Participant gender:
All
Summary
Vitamin D has been known to influence immune response through Vitamin D Receptor in Immune Cells, but only few has been known about the effect alfacalcidol, a vitamin D analog to immune system. In elderly, immune disregulation or immunosenecence have great impact to infection response. This study is aimed to determine the effect of alfacalcidol supplementation in vitro and in vivo to respiratory infection incidence and inflammatory markers, as well as T cell lymphocyte subset in Indonesian elderly patients.
Phase:
Phase 4
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Indonesia University
Treatments:
Alfacalcidol
Cholecalciferol
Hydroxycholecalciferols
Criteria
Inclusion Criteria:

- Elderly age more than 60

- Willing to join research

Exclusion Criteria:

- In acute infection

- Using NSAID or steroid

- Liver failure

- Hypercalcemia