Overview

Effect of Adding Lactoferrin on Oral Iron on Anemia in Chronic Kidney Disease Patients

Status:
Recruiting

Trial end date:
2023-09-01

Target enrollment:
0

Participant gender:
All

Summary

The aim of this study is to evaluate the effects of adding lactoferrin to the every-other-day oral iron supplementation in iron deficiency anemia and chronic kidney disease patients.

Phase:

Phase 4

Accepts Healthy Volunteers?

Details

Lead Sponsor:

Alexandria University

Treatments:

Glycine
Lactoferrin

Criteria

Inclusion Criteria:

1. Males and Females aged ≥ 18 years old

2. Patients with eGFR ≥30 and ≤60 mL/min/1.73m2.

3. Absolute iron deficiency anemia (Hgb <10g/dL, serum ferritin <300ng/ml and Transferrin
Saturation < 30% )

Exclusion Criteria:

1. Patients on intermittent hemodialysis (IHD)

2. Patients with any known cause of anemia other than iron deficiency or CKD (e.g.,
sickle cell anemia)

3. Patients who received EPO 4 weeks ago

4. Patients who received IV Iron 8 weeks ago

5. Patients who received blood Transfusion 8 weeks ago

6. Current history of GI bleeding

7. Malignancy history

8. Pregnancy or lactation in female participants

9. Patients non-adherent to at least 80% of the regimen