Effect of Acetazolamide on Subclinical High-Altitude Pulmonary Edema Detected by Lung Ultrasonography

• Status: Terminated
• Trial end date: 2018-04-04
• Target enrollment: 0
• Participant gender: All

Summary

The overall goal of this study is to detect preclinical signs of HAPE by lung ultrasonography and evaluate the effectiveness of acetazolamide at decreasing pulmonary edema by using ultrasound.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Vincent Kan
• Treatments: Acetazolamide

Criteria

Inclusion Criteria:

1. At least 18 years of age

2. Able to consent

3. English speaking

4. Trekking directly to Everest Base Camp

Exclusion Criteria:

1. Age less than 18 years

2. Non-English speaking

3. Pregnant

4. Already had a diagnosis of acute mountain sickness, high-altitude cerebral edema, or high-altitude pulmonary edema

5. Been on a high-altitude trek 2 weeks prior to this study

6. Has taken acetazolamide 1 week prior to start of trek

7. Has a sulfa allergy

8. Has any type of acute or chronic pulmonary conditions