Overview

Effect of AD128 to Treat Obstructive Sleep Apnea

Status:
Completed
Trial end date:
2021-07-19
Target enrollment:
Participant gender:
Summary
This study evaluates the combination of two drugs (AD128), to treat obstructive sleep apnea (OSA) severity. After a baseline evaluation and during 7 days, half of the participants will randomly receive this drug combination (AD128) and the other will receive a placebo, i.e. a drug without pharmaceutical effect. Neither the participants, nor the investigators will know in which arm participants are until the end of the study. After one week of trial, an evaluation will be perform and will be follow by one week without any treatment. During the third and last week of trial, there will be a crossover of the groups, i.e. the participants of the first group who took the two drugs (AD128) during the first week will take a placebo and those who took the placebo will take the drugs combination.
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
Raphael Heinzer
Collaborator:
Apnimed
Treatments:
Mannitol
Oxybutynin
Reboxetine