Effect of 4 Weeks Treatment With Acipimox in Patients With Chronic Heart Failure

• Status: Completed
• Trial end date: 2009-05-01
• Target enrollment: 0
• Participant gender: All

Summary

The primary objective of this study is to evaluate whether metabolic modulation improves left ventricular function, work capacity, insulin sensitivity and modifies substrate metabolism in chronic heart failure

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Aarhus
• Treatments: Acipimox

Criteria

Inclusion Criteria:

• EF<40 %

• IHD

• NYHA-class II-III.

Exclusion Criteria:

• pregnancy

• severe renal failure

• new brady- or tachyArrhythmia

• Severe stenotic valvular disease

• myocardial infarction within last 6 weeks

• insulin treated diabetes mellitus

• peptic ulcer

• pregnancy or lactating women

• allergy towards tested medicine