Effect of 25-hydroxyvitamin D and a Structured Exercise Program on Dialysis Patients

• Status: Completed
• Trial end date: 2011-09-01
• Target enrollment: 0
• Participant gender: All

Summary

This study aims to examine the effect of 25 hydroxyvitamin D supplementation and a structured exercise program on the exercise capacity and quality of life of haemodialysis patients with 25 hydroxyvitamin D insufficiency.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Sir Charles Gairdner Hospital
• Treatments: Calcifediol; Cholecalciferol; Hydroxycholecalciferols; Vitamin D

Criteria

Inclusion Criteria:

1. Stable on dialysis for at least 3 months

2. Able to obtain informed consent

3. Medically stable

4. Dialysis adequacy at target for small solute clearance (ie Kt/V>1.2 or Urea reduction ratio>65%)

5. Serum 25-hydroxyvitamin D levels less than 75nmol/L at baseline

Exclusion Criteria:

1. Limb Amputation

2. Impaired cognition

3. Impaired vision

4. Haemoglobin concentration < 110g/L

5. Change in Erythropoiesis stimulating agent dose over the last 2 months

6. Unable or unwilling to comply with exercise program