Edaravone on the Ischemia-Reperfusion(I/R) Injury in Kidney Transplantation Patients
Status:
Unknown status
Trial end date:
2016-10-01
Target enrollment:
Participant gender:
Summary
Ischemia-reperfusion (I/R) injury is a prominent cause of delayed graft function(DGF) after
kidney transplantation. Reactive oxygen species play a crucial role in I/R injury. Edaravone
is a synthetic radical scavenger that has been used in acute stroke. Some animal experiments
have revealed its beneficial effects against I/R injury, our goal is therefore to investigate
the effectiveness of a recipient pretreatment with Edaravone at reducing the occurrence of
DGF after kidney transplantation.
Phase:
N/A
Details
Lead Sponsor:
Xijing Hospital
Collaborator:
First Affiliated Hospital Xi'an Jiaotong University