Eclampsia and Posterior Reversible Encephalopathy Syndrome (PRES):
Status:
Terminated
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
This is a double blinded, placebo-controlled trial to determine if IV dexamethasone more
quickly than placebo assists resolution of Posterior Reversible Encephalopathy Syndrome
(PRES) encountered in eclamptic patients. All patients regardless of assignment to placebo or
steroid will receive standard therapy to include magnesium sulfate, blood pressure
medications and diuretics. We hypothesize that the addition of dexamethasone to standard
therapy will accelerate CNS recovery more quickly than standard management without
dexamethasone.