Early vs Postponed Parenteral Nutrition After Emergency Abdominal Surgery
Status:
Recruiting
Trial end date:
2026-01-01
Target enrollment:
Participant gender:
Summary
The aim of this study is to investigate the effect of early, supplementary parenteral
nutrition following emergency laparotomy.
Currently, parenteral nutrition is used in postoperative patients if or when oral or enteral
nutrition is not feasible. However, little data exists on the optimal timing of parenteral
nutrition.
Oral and enteral nutrition is encouraged. Participants will randomized on the second
postoperative day if their calorie intake (oral + enteral) is below 30% of the calculated
requirement. Patients will be randomized to early (postoperative day 2) or postponed
(postoperative day 5) start of parenteral nutrition.
The combined oral + enteral + parenteral calorie target is 70-80% of the calculated
requirement. Participants in the postponed group will be re-assessed on postoperative day 5,
and if their calorie intake is less than 50% parenteral nutrition will be administered.
The intervention will continue until oral + enteral intake is at least 70% of the calculated
requirement or the participant is at his/her habitual intake.
Phase:
Phase 4
Details
Lead Sponsor:
Copenhagen University Hospital at Herlev
Collaborators:
Copenhagen University Hospital, Hvidovre Nordsjaellands Hospital Slagelse Sygehus