Overview

Early Statin-Ezetimibe Combination vs. Statin Monotherapy in Stroke With Atherosclerosis

Status:
RECRUITING
Trial end date:
2029-07-31
Target enrollment:
Participant gender:
Summary
This study will be conducted at six medical institutions in Taiwan, recruiting patients who visit neurology outpatient clinics or are hospitalized within 30 days after an ischemic stroke. Participants will be randomly assigned to either the experimental group (moderate-intensity statin plus ezetimibe) or the control group (moderate- or high-intensity statin). Research assistants will screen patients aged 40 or older who have had an ischemic stroke or transient ischemic attack within 30 days, have atherosclerosis, and have LDL-C levels 100 mg/dL. Eligible cases will be reviewed by the attending physician. With physician approval, patients will be invited to join the study, and those who agree and sign informed consent will be enrolled.
Phase:
PHASE2
Details
Lead Sponsor:
Chang Gung Memorial Hospital
Collaborator:
Chang Gung University
Treatments:
Atorvastatin
Ezetimibe
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Rosuvastatin Calcium