Early Resuscitation in Paediatric Sepsis Using Inotropes
Status:
NOT_YET_RECRUITING
Trial end date:
2025-12-01
Target enrollment:
Participant gender:
Summary
Septic shock in children still carries substantial mortality and morbidity. While resuscitation with 40-60 mL/kg intravenous fluid boluses remains a cornerstone of initial resuscitation, an increasing body of evidence indicates potential for harm related to high volume fluid administration. The investigators hypothesize that a protocol on early use of inotropes in children with septic shock is feasible and will lead to less fluid bolus use compared to standard fluid resuscitation. Here, the investigators describe the protocol of the Adrenaline in Early Sepsis Resuscitation in Children- A Randomised Controlled Pilot Study in the Emergency Department (ANDES CHILD)
Phase:
PHASE2
Details
Lead Sponsor:
NATALIA LOPERA MUNERA
Collaborators:
Hospital Pablo Tobón Uribe Instituto Latino Americano de Sepse Universidad Nacional del Nordeste, Argentina University Children's Hospital, Zurich