Early Predictor of Herceptin Cardio Toxicity in Breast Cancer Patients
Status:
Suspended
Trial end date:
2016-08-01
Target enrollment:
Participant gender:
Summary
Early identification of patients at risk for cardiotoxicity represent a primary goal for
cardiologist and oncologist
From all adjuvant trials echocardiography is ideal for evaluating Left Ventricular function
though its operator dependent. The use of other technique such as endomyocardial biopsy, is
troublesome in clinical practice
Cardiac magnetic resonance imaging (MRI) have greater reproducibility in evaluating left
ventricular ejection fraction (LVEF). This technique provides morphological, functional,
perfusion, and viability information in one assessment. It is expensive and time consuming
but id the diagnostic method of choice for patients with technically limited images from ECG
and in patients with discordant information that is clinically significant from prior tests