Early Phase II Trials for Cocaine Medication Development - 1
Status:
Completed
Trial end date:
1999-07-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to develop models for early Phase II testing of potential
medications for cocaine dependence: amoxapine, risperidone and other agents.
The study was a controlled pilot trial of risperidone in opiate-dependent patients on
methadone maintenance. The study explored whether risperidone reduced cocaine use, cocaine
craving, and cocaine subjective effects in patients on methadone maintenance who abused
cocaine and whether it had an acceptable side effect profile. This
Phase:
Phase 2
Details
Lead Sponsor:
New York State Psychiatric Institute
Collaborators:
National Institute on Drug Abuse (NIDA) Research Foundation for Mental Hygiene, Inc.